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<!DOCTYPE html>
<html>
<head>
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<title>Nikolaos Dimitriou</title>
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<div id="mySidenav"; class="sidenav">
<a href="javascript:void(0)" class="closebtn" onclick="closeNav()">×</a>
<a href="#bio">Bio</a>
<a href="#publications">Publications</a>
<a href="#teaching">Teaching</a>
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<h1>Nikolaos Dimitriou, PhD</h1>
<h2>Memorial Sloan Kettering Cancer Center</h2>
</div>
<main onclick="closeNav()"; id="main">
<section id="bio" class="bio-section" style="margin-top: 200px; width: 100%">
<div>
<h3>Bio</h3>
<p>Nikolaos (Nikos) is a research fellow in the Carrot-Zhang lab at the Dept. of Computational
Oncology of Memorial Sloan Kettering Cancer Center. His research focuses on identifying
the interactions between driver mutations and ancestry related traits in cancer,
genotype-phenotype mapping, as well as the role of race/ethnicity in tumor treatment
response.</p>
<p>Nikos is a PhD of the Department of Bioengineering at McGill where he worked on
mathematical modelling of cancer growth, supervised by Prof. Georgios Mitsis.
His research aimed to uncover and quantify the underlying
biophysical mechanisms of cancer growth using mathematical models and 3D cell culture experiments.
During his PhD studies, he focused on (1) validating hybrid multiscale models with
3D cell culture data, (2) the investigation of sedimentation phenomena in 3D hydrogel cultures, and (3)
the design of multiscale models by combining tumour growth and the expression profiles of genes
related to drug resistance. He was also the recipient of the prestigious
Stavros Niarchos, and Werner Graupe fellowships.</p>
<p>Nikos' undergraduate studies took place at National Technical University of Athens. He obtained a Diploma in
Applied Mathematics and Physics with a focus on theoretical, particle and computational physics. Even though the study
curriculum of his undergraduate School was not directly related to biology, it allowed him to take courses related to
Theoretical Physics which provided a solid mathematical and computational background, as well as analytical reasoning
skills that are generally applicable. From the 3rd year of his studies, he developed an interest in cancer which enabled
him to design research projects on nanoparticle therapies.
</p>
</div>
<div class="bio-photo">
<img src="images/original/IMG_20230511_143559_791.jpg">
</div>
</section>
<section id="publications">
<h3>Publications</h3>
<h4 class="publications-heading">Preprints</h4>
<ol class="publications-list">
<li>
<h5 class="publications-title">A calibration and uncertainty quantification analysis of classical, fractional
and multiscale logistic models of tumour growth.</h5>
<p class="journal-info">Dimitriou, N. M., Demirag, E., Strati, K., & Mitsis, G. D.</p>
<p>BioRxiv (2023). <a href="https://doi.org/10.1101/2023.04.12.536622"> Link to preprint. </a> <span class="__dimensions_badge_embed__" data-doi="10.1101/2023.04.12.536622" data-hide-zero-citations="true" data-style="large_rectangle"></span> </p>
</li>
<li>
<h5 class="publications-title">Cancer cell sedimentation in 3D cultures reveals active migration
regulated by self-generated gradients and adhesion sites.</h5>
<p class="journal-info">Dimitriou, N. M., Flores-Torres, S., Kyriakidou, M., Kinsella, J. M., & Mitsis, G. D.</p>
<p>BioRxiv (2023). <a href="https://doi.org/10.1101/2023.02.15.528731"> Link to preprint. </a>
<span class="__dimensions_badge_embed__" data-doi="10.1101/2023.02.15.528731" data-hide-zero-citations="true" data-style="large_rectangle"></span></p>
</li>
</ol>
<h4 class="publications-heading">Journal Articles</h4>
<ol class="publications-list">
<li>
<h5 class="publications-title">Bioprinted Multicomponent Hydrogel Co-culture Tumor-Immune Model for Assessing and Simulating
Tumor-Infiltrated Lymphocyte Migration and Functional Activation.</h5>
<p class="journal-info">Flores-Torres, S., Dimitriou, N. M., Pardo, L. A., Kort-Mascort, J., Pal, S., Peza-Chavez, O., Kuasne,
H., Berube, J., Bertos, N., Park, M., Mitsis, G. D., Ferri, L., Sangwan, V., & Kinsella, J. M.</p>
<p>ACS Applied Materials & Interfaces (2023).
<a href="https://doi.org/10.1021/acsami.3c02995"> Link to publication.</a>
<span class="__dimensions_badge_embed__" data-doi="10.1021/acsami.3c02995" data-style="large_rectangle"></span></p>
</li>
<li>
<h5 class="publications-title">Quantifying the Morphology and Mechanisms of Cancer Progression in 3D in-vitro environments: Integrating Experiments
and Multiscale Models.</h5>
<p class="journal-info">Dimitriou, N. M., Flores-Torres, S., Kinsella, J. M., & Mitsis, G. D.</p>
<p>IEEE Transactions on Biomedical Engineering (2022). <a href="https://doi.org/10.1109/TBME.2022.3216231"> Link to publication. </a>
<a href="https://www.biorxiv.org/content/10.1101/2021.11.16.468856v9"> Link to preprint. </a>
<span class="__dimensions_badge_embed__" data-doi="10.1109/TBME.2022.3216231" data-style="large_rectangle"></span></p>
</li>
<li>
<h5 class="publications-title">Detection and Spatiotemporal Analysis of In-vitro 3D Migratory
Triple-Negative Breast Cancer Cells. Annals of Biomedical Engineering.</h5>
<p class="journal-info">Dimitriou, N. M., Flores-Torres, S., Kinsella, J. M., & Mitsis, G. D.</p>
<p>Annals of Biomedical Engineering (2022). <a href="https://doi.org/10.1007/s10439-022-03022-y">Link to publication. </a>
<a href="https://t.co/k1btdPEYG4"> Link to PDF. </a>
<span class="__dimensions_badge_embed__" data-doi="10.1007/s10439-022-03022-y" data-style="large_rectangle"></span></p>
</li>
<li>
<h5 class="publications-title">Prediction of Gold Nanoparticle and Microwave-Induced Hyperthermia
Effects on Tumor Control via a Simulation Approach.</h5>
<p class="journal-info">Dimitriou, N. M. N. M., Pavlopoulou, A., Tremi, I., Kouloulias, V., Tsigaridas, G., & Georgakilas, A. G.</p>
<p>Nanomaterials 9(2) (2019). <a href="https://doi.org/10.3390/nano9020167">Link to publication. </a>
<span class="__dimensions_badge_embed__" data-doi="10.3390/nano9020167" data-style="large_rectangle"></span></p>
</li>
<li>
<h5 class="publications-title">Gold nanoparticles, radiations and the immune system: Current insights into the physical mechanisms and the biological interactions of this new alliance
towards cancer therapy.</h5>
<p class="journal-info">Dimitriou, N. M., Tsekenis, G., Balanikas, E. C., Pavlopoulou, A., Mitsiogianni, M., Mantso,
T., Pashos, G., Boudouvis, A. G., Lykakis, I. N., Tsigaridas, G., Panayiotidis, M. I., Yannopapas,
V., & Georgakilas, A. G.</p>
<p>Pharmacology and Therapeutics, 178, 1–17 (2017). <a href="https://doi.org/10.1016/j.pharmthera.2017.03.006">Link to publication. </a>
<span class="__dimensions_badge_embed__" data-doi="10.1016/j.pharmthera.2017.03.006" data-style="large_rectangle"></span></p>
</li>
</ol>
</section>
<section id="teaching">
<h3>Teaching</h3>
<ul class="publications-list">
<li>
<p>Biological Transport Phenomena 2 (BIEN 340), TA, Instructor: Dr. Lawrence Oprea (2023)</p>
</li>
<li>
<p>Engineering Principles in Physiological Systems (BIEN 462), TA, Instructor: Prof. Charles Capaday (2022)</p>
</li>
<li>
<p>Biosignals and Systems and Control (BIEN 350), TA, Instructors: Prof. Charles Capaday, Georgios Mitsis (2021-2022)</p>
</li>
</ul>
</section>
<section id="gallery" style="z-index: 5">
<h3>Gallery</h3>
<div class="image-grid" style="width:80vw; height:auto">
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<img src="images/thumbs/MG_4989test_thumb.jpg" onclick="openModal();currentSlide(19)" class="hover-shadow cursor">
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<img src="images/original/MG_6851.jpg" alt="Vikos canyon, Beloi, Greece, 2022">
<div class="caption">Vikos canyon, Beloi, Greece, 2022</div>
</div>
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<img src="images/original/MG_6864.jpg" alt="Misiou ancient stone bridge, Voidomatis river, Greece, 2022">
<div class="caption">Misiou ancient stone bridge, Voidomatis river, Greece, 2022</div>
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<img src="images/original/MG_6892.jpg" alt="Kapesovo village, Greece, 2022">
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<img src="images/original/MG_6903.jpg" alt="One of the hundreds ancient stone bridges of Ioannina, Greece, 2022">
<div class="caption">One of the hundreds ancient stone bridges of Ioannina, Greece, 2022</div>
</div>
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<img src="images/original/MG_6946.jpg" style="width: 30vw;" alt="Iliochori village, Greece, 2022">
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<img src="images/original/pan.jpg" alt="Vikos canyon, Panoramic view from Holy Monastery of Saint Paraskevi, Greece, 2022">
<div class="caption">Vikos canyon, Panoramic view from Holy Monastery of Saint Paraskevi, Greece, 2022</div>
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<img src="images/original/MG_6954.jpg" alt="Athens, Greece, 2022">
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<img src="images/original/MG_6730.jpg" style="width: 30vw;" alt="Vancouver, Seaplanes, Canada, 2022">
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